Nasal Sores in Systemic Lupus Erythematosus: Clinical Features and Diagnostic Significance
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse mucocutaneous manifestations. Nasal sores—mucosal ulcers or crusted lesions within the nasal vestibule—are a recognized but often underreported feature. They fall under the American College of Rheumatology (ACR) criteria for SLE (oral or nasal ulcers). nose sores lupus pictures
Lupus nasal ulcers show interface dermatitis, lymphocytic infiltration, basement membrane thickening, and direct immunofluorescence (positive lupus band test in lesional skin). basement membrane thickening