Abstract Kerley C lines are a lesser-known but important radiographic sign of interstitial pulmonary edema. Unlike the more commonly recognized Kerley A and B lines, C lines are fine, reticular opacities predominantly seen in the lower and mid-zones of the lungs. This paper reviews their historical context, anatomical-pathological correlation, radiographic identification, and clinical relevance, emphasizing their role in the early detection of elevated pulmonary capillary wedge pressure.
First described by the Irish radiologist Peter Kerley in the 1930s, Kerley lines are linear opacities seen on chest radiographs of patients with pulmonary venous hypertension. While Kerley A lines (long, linear opacities radiating from the hila) and Kerley B lines (short, horizontal lines at the lung bases) are well-documented, Kerley C lines are often overlooked or mischaracterized. Understanding all three patterns is crucial for accurate interpretation of interstitial lung fluid. kerley c line